side effect of justicia carnea

This information may not fit your specific health circumstances. Justicia carnea (belonging to Acanthaceae family) is a flowering plant consisting ~600 species that are widely distributed in the tropics and subtropics [7]. 2015;174:61827 https://doi.org/10.1016/j.jep.2015.06.005. The changing faces of glutathione, a cellular protagonist. Google Scholar. How to make Ewe eje Extracthow to prepare justicia carnea. Justicia pectoralis is a flowering herb that grows in tropical areas of the Americas, including South and Central America. 5. Nutritive properties of aqueous extract Justicia carnea leaves and its effects on haematological and some biochemical indices of anaemia induced male wistar albino rats. Photomicrograph of liver sections stained with haematoxylin and eosin (H & E) are presented in Fig. The findings back up local assertions that they can be. J Med Plants Res. https://doi.org/10.35841/biomedicalresearch.30-18-666. 3rd ed. The plant, which is usually green in color and produces pink flowers, belongs to the family of Acanthaceae. Effect of the ethanol extract of Justicia carnea leaves on the red It is also known as Jacobinia carnea, and is a part of the Acanthaceae family along with the Aphelandra squarrosa (Zebra plant) and Crossandra. Justicia carnea [jus-TEE-see-ah, KAR-nee-uh] is popularly known as the Brazilian Plume Flower. Rather it can assist with improveing liver function such as detoxification. Data were analyzed using one-way analysis of variance (ANOVA) using Statistical Product and Service Solutions (SPSS) version 17.0 and results were expressed as meanSEM. Valko M, Leibfritz D, Moncol J, Cronin MTD, Mazur M, Telser J. To create additional collections, you must be a paid member of our site. Tips on how to get rid of leaf eating caterpillar. J Ethnopharmacol. Medapa S, Singh GRJ, Ravikumar V. The phytochemical and antioxidant screening of Justicia wynaadensis. One of the numerous nutritional benefits of justicia carnea leaves is in the possession of various forms of the B vitamins such as Vitamin B1, B2, B6, B9, and B12. 2019;30(4):64554. The shrubby habit of the plant is well-suited for both containers and outside planting. Add organic matter or compost in the soil and place the plant. 2016;5(1):6270 https://doi.org/10.1016/j.joad.2015.08.006. Despite the therapeutic importance of medicinal plants, toxic substances have been shown to be present in large numbers of plants investigated [3]. Tropical habitats mean constant moisture. In these groups, from mild to severe order; the renal cortex appears distorted, Renal glomeruli and dillated capsular spaces appeared collapsed with characteristic pyknosis of the mesangial cells, The renal tubules, interstitial spaces, appears distorted with presence of red inflammatory cells, hemorrhagic cells infiltrating the renal interstitial spaces as well as focal sclerosis of renal glomeruli with associated degeration of the glomerular membrane (red arrows). The renal cortex showed normal glomeruli with mesangial cells and capsular spaces appeared normal (white arrow), the renal tubules appear normal (blue arrow) and interstitial spaces also observed normal (black arrow). White blood cell counts usually increases following foreign invaders (pathogens) resulting in normal body physiological response which boost the bodys defense mechanisms [28, 29]. 2023 BioMed Central Ltd unless otherwise stated. Mean lethal dose of the extract was found to be above 5000mg/kg body weight (bw). Sinha AK. PDF Evaluation of Anti-inflammatory and Analgesic Properties of Justicia Ewe eje improves the production of white blood cells and other antibodies, all which are essential for strengthening immunity. View abstract. They are also needed in strong bone formation, and in cellular and neuronal functions. Plantcaretoday.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to amazon.com, how to get rid of leaf eating caterpillar. Phytochemical profile, antioxidant, -amylase inhibition, binding Ewe eje is safe and healthy for consumption. These antibodies help prevent infections and fight off diseases. A multidisciplinary overview of intoxicating snuff rituals in the western hemisphere. Higher doses (>500mg/kg) of extract significantly (p<0.05) increased RBC, hemoglobin and platelet compared to the control. The indistinguishable differences of total protein in the liver and kidney of rats treated with ethanol extract of J. carnea could indicate that the plant extract did not alter protein synthetic function of the organs. Also present in the leaf extract are minerals (such as magnesium, copper, iron, zinc, calcium); and vitamins (such as vitamins A, C, E and B-vitamins). Extraction was carried out by maceration (72h) following the method of Onoagbe et al., [13]. This plant is somewhat drought-tolerant once established but looks best with regular watering during periods of extended dry weather. Prepare the existing soil by breaking it up with a spade or hoe. CAS Venancio, E. T., Rocha, N. F., Rios, E. R., Feitosa, M. L., Linhares, M. I., Melo, F. H., Matias, M. S., Fonseca, F. N., Sousa, F. C., Leal, L. K., and Fonteles, M. M. Anxiolytic-like effects of standardized extract of Justicia pectoralis (SEJP) in mice: Involvement of GABA/benzodiazepine in receptor. The red coloration of the decoction made people think that the plant must contain blood boosting compounds. Nigeria's medicinal plant: Justicia carne (Ewe eje) - PressReader Mr. T.S. Justicia carnea is a medicinal plant that is used conventionally as blood tonic from time immemorial in Nigeria. 2013;1:38898. In-vitro Antioxidant Screening of Ethanol Extracts of Costus afer and Authors TSO, KOK and ESA manage experimental protocols and performed the experiments under the supervision of FOA. The genus Justicia named after the 18th-century Scottish botanist James Justice is a flowering plant in the family Acanthaceae. It creates the perfect environment for aphids and dried sod. By using this website, you agree to our View abstract. The compound responsible for this activity is lignan. Akintimehin, E.S., Karigidi, K.O., Omogunwa, T.S. In these groups, from mild to severe order; shows observable congested portal vein, the liver parenchyma showed area of harmorrhage, the morphology of the hepatocytes appear pyknotic, some show mild fat infiltration (red arrow) the sinusoids appear fibrotic with infiltration of inflammatory red cells (red arrow). Great for use as a foundation or mass planting, it is also terrific for containers or as a houseplant. Too much sun can scorch the leaves, and too little will result in fewer flowers. Akintimehin is a lecturer in the Biochemistry unit of Chemical Sciences Department, Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State, Nigeria. View abstract. The resultant liquid would turn crimson red. Turn off the heat and then soak the leaves into the pot. Safety assessment of oral administration of ethanol extract of, $$ \mathrm{Total}\ \mathrm{protein}\kern0.5em =\kern0.5em \frac{\mathrm{Absorbance}\ \mathrm{of}\ \mathrm{sample}}{\mathrm{Absorbance}\ \mathrm{of}\ \mathrm{standard}}\kern0.5em \times \kern0.5em \mathrm{Concentration}\ \mathrm{of}\ \mathrm{standard} $$, $$ \mathrm{Catalase}\ \mathrm{activity}\ \left(\mathrm{U}/\mathrm{ml}\right)=\kern0.5em \frac{\Delta \mathrm{A}/\min \kern0.5em \times \kern0.5em \mathrm{TV}}{\upvarepsilon \kern0.5em \times \kern0.5em \mathrm{SV}\kern0.5em \times \kern0.5em \mathrm{TP}} $$, $$ \mathrm{SOD}\ \mathrm{activity}\ \left(\mathrm{U}/\mathrm{ml}/\mathrm{mg}\ \mathrm{protein}\right)\kern0.5em =\kern0.5em \frac{\Delta \mathrm{A}/\min \kern0.5em \times \kern0.5em \mathrm{TV}}{\upvarepsilon \kern0.5em \times \kern0.5em \mathrm{SV}\kern0.5em \times \kern0.5em \mathrm{TP}} $$, $$ \mathrm{Concentration}\kern0.5em \mathrm{of}\kern0.5em \mathrm{reduced}\kern0.5em \mathrm{GSH}\kern0.5em =\kern0.5em \frac{\left(\Delta \mathrm{A}\kern0.5em \times \kern0.5em \mathrm{TV}\right)}{\left(\upvarepsilon \kern0.5em \times \kern0.5em \mathrm{SV}\kern0.5em \times \kern0.5em \mathrm{TP}\right)} $$, $$ \mathrm{Malondialdehyde}\kern0.5em =\kern0.5em \frac{\left(\mathrm{A}\kern0.5em \times \kern0.5em \mathrm{TV}\right)}{\Big(\upvarepsilon \kern0.5em \times \kern0.5em \mathrm{SV}\kern0.5em \times \kern0.5em \mathrm{TP}} $$, https://doi.org/10.1186/s40816-020-00234-4, https://doi.org/10.1016/j.jep.2015.06.005, https://doi.org/10.1016/j.joad.2015.08.006, https://doi.org/10.1016/j.jep.2005.06.013, https://doi.org/10.3109/08860220903367585, https://doi.org/10.1590/S0102-695X2011005000196, https://academicjournals.org/journal/AJPS/article-full-text-pdf/6AA410310867, https://doi.org/10.35841/biomedicalresearch.30-18-666, https://doi.org/10.1016/j.jep.2007.02.011, https://doi.org/10.1186/s40816-019-0104-4, https://doi.org/10.1016/j.fitote.2008.02.005, https://doi.org/10.1016/j.jada.2008.06.430, https://doi.org/10.1016/j.biocel.2006.07.001, https://doi.org/10.1186/s12906-015-0760-y, http://creativecommons.org/licenses/by/4.0/. It does not tolerate low temperatures at all. Studies have shown that ewe eje isnt capable of causing damage to the liver. The antioxidants in Justicia carnea helps protect the liver and the heart from toxic agents and free radicals. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. Luckily, the unique flowers of Jacobinia carnea and its foliage are free from major pest and disease concerns. In sub-acute toxicity study, total of thirty (30) rats were randomized into six groups of five rats per group: Group 1 served as control and was administered with 1ml of distilled water (dH2O). These compositions (metabolites and nutrients) are all responsible for the medicinal value and the health benefits of Justicia carnea. 34-45. Differences between means were considered to be significant at (p<0.05) using LSD (Least Square Difference) post hoc test. Therapeutic Research Faculty 2020. The liver and kidney of rats administered with 500mg/kg JCEE and above demonstrated slight increase in MDA level with significant (P<0.05) increase only observed in the liver of rats that received 1200mg/kg of extract. Arch Toxicol. Brazilian-plumeflowers are best propagated from softwood cuttings. This encourages better flowering and bushier and denser new growth. I do hope that after reading through this article, you would plan to start cultivating this amazing plant specie in your garden. The plant possess several bioactive compounds like polyphenols, which act as antioxidants or anti-inflammatory compounds. This amazing, Coriander seeds as well as the leaves are widely used as spices in flavoring foods and drinks, and, Cashew leaves: health benefits and side effects of Anacardium occidentale, Fig leaves tea: Amazing benefits and best recipes, Negro pepper: 12 health benefits of uda seed and side effects. The cuttings should be placed in individuals pots and put under glass or shaded location, away from direct sunlight. Google Scholar. The ability of glutathione to regenerate these dietary antioxidants has been linked to the redox state of glutathione disulphide-glutathione couple (GSSG/GSH) ratio [31]. African J Plant Sci. Blooming from early summer to fall, the flowers are attractive to hummingbirds and butterflies. Previously, J. carnea leaf has been reported to contain high quantity of phytochemical constituents (such as saponins, alkaloids and terpenoids), vitamins (A, C and E) and minerals [9, 10]. In a pot, pour in a cup of water and bring to a boil. Different researches performed on wistar rats has proven the non toxicity of justicia carnea. The presence of blood boosting nutrients such as iron, copper, zinc and vitamin C can help prevent iron-deficiency anaemia and other anemic conditions. Haematological and biochemical studies on Justicia carnea leave extract in phenylhydrazine induced-anemia in albino rats. J. Pharmacogn. Braz. Meth Enzymol. II. View abstract. It may also affect the activity of hormones. Names of Justicia Betonica in various languages of the world are also given. The non significant decrease observed in this study is in consonance with the work of Onyeabo et al., [9] who also reported no significant difference in the relative weights of liver and kidney. Pompella A, Visvikis A, Paolicchi A, De Tata V, Casini AF. This study has confirmed the safety of ethanol extract of J. carnea leaf and validates its conventional use as blood booster. The leaves are also rich source of vitamin A, vitamin C, and vitamin E. Another plant with this composition is pumpkin fruit. Becoming a contributing member of Gardenia is easy and can be done in just a few minutes. de Vries, J. X., Tauscher, B., and Wurzel, G. Constituents of Justicia pectoralis Jacq. 1978;90:819. By entering your email address you agree to receive a daily email newsletter from Plant Care Today. 2007;39(1):4484. The Health benefit of Ewe eje (Justicia carnea leaf) are highlighted in this article. It is also known as Jacobinia carnea, and is a part of the Acanthaceae family along with the Aphelandra squarrosa (Zebra plant) and Crossandra. Clin Phytosci 7, 2 (2021). Sample (or standard solution) (0.01ml) was mixed with diluted (1:4v/v distilled water) biuret reagent (100mM sodium hydroxide, 16mM sodium-potassium tartrate, 15mM potassium iodide and 6mM copper sulphate). Treatments of all experimental animals were performed following Principle of Laboratory Animal Care manual guidebook of National Institute of Health as approved by the Research Ethics Committee of Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State. It results from one or more of the following events: loss of red blood cells (RBCs), reduction in the production of RBCs, increased destruction of RBCs, and shorter life span of RBCs (McEvoy, 2013). Backfill the soil gently, filling the empty space around the root ball and then press it down with your hands. https://doi.org/10.13040/IJPSR.0975-8232. Anti-obesity, antioxidant and in silico evaluation of Justicia carnea It is obvious that Justicia carnea has potential antianemic, antioxidant, antidiabetic, hepatoprotective, and immune-boosting properties. Justicia carnea - Wikipedia -Amylase binding-interaction with JCAE was also investigated using fluorescence spectroscopy and molecular docking. The unique flower clusters and bright coloring has made it a popular choice among landscape artists and amateur gardeners as well. Decreased white blood cell count was obtained in this report, the level of lymphocyte and granulocyte was not altered by the extract while MID sized cell was significantly elevated at 500 and 800mg/kg dose. Anti-depressant-like effect of kaempferitrin isolated from Justicia spicigera Schltdl (Acanthaceae) in two behavior models in mice: evidence for the involvement of the serotonergic system. PDF Journal La Lifesci Molecules (Basel, Switzerland), 19(12), 2144221461. 2003;66:1499503. Justicia carnea has been used in traditional medicine to treat diabetes. The acute toxicity test also proved that justicia carnea leaves are safe for consumption. These compounds beyond boosting your blood concentration, thereby enhancing the transport of nutrients to various parts of the body, also boost your immune system against several infectious diseases. This could possibly indicate SOD stimulating effects of J. carnea leaf ethanol extract. Current School News This also helps prevent self-seeding, which normally takes up a lot of the plants energy at the expense of flowering. At this time there is not enough scientific information to determine an appropriate range of doses for Justicia pectoralis. Hence, Justicia carnea can be used to strengthen the immune system. The roots and the leaves possess medicinal values and have been used in treating several diseases. How often should it be watered? You can add milk or honey for taste before drinking. Adetuyi is a Professor of Biochemistry in the Department of Chemical Sciences, Faculty of Sciences, Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State, Nigeria. Methods. This is due to the inability of the pancreatic beta cells to secrete insulin, which transports glucose to cells, or the inability of cells of the body to recognize insulin. CAS Accept Biochem Pharmacol. Niger J Physiol Sci. In various parts of Africa, several species of Justicia are used in traditional medicine for the treatment of anemia, inflammation, fever, diarrhea, liver diseases and arthritis respiratory and gastrointestinal disorder [8, 9]. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Justicia carnea is a popular ornamental plant, which possesses powerful medicinal values. Justicia carnea (Brazilian Plume) is an upright, evergreen shrub with large, dark green leaves, 10 in. How Justicia Betonica is effective for various diseases is listed in repertory format. California Privacy Statement, Article Microsomal lipid peroxidation. Emmanuel Sina Akintimehin. The plant is hardy to USDA Hardiness Zones 8b through 11. Article 4. Despite the use of Justicia carnea and other reported scientific studies, there are no reports on its effects on the major organs of the body. Side effects of Ewe eje (Justicia carnea leaf Side Effects). 3 . Justicia carnea needs bright, indirect light to thrive. View abstract. Lipid peroxidation was determined by measuring the formation of thiobarbituric acid reactive substances (TBARS) according to the method described by Buege and Aust [20]. Tissues were processed automatically using automatic tissue processor (Leica TP 1020) and allowed to pass through varying percentage of alcohol and absolute alcohol for the purpose of dehydration following dewaxing in Xylene for 15mins. Growing up, we were told many biblical stories, Negro pepper (Xylopia aethiopica) is a spice plant that possess several health benefits, which make it an indispensable, Eating for its sour taste when fairly ripen and sweet taste when well ripen, star apple finds favor, Fertility tree (Newbouldia laevis), also known as boundary tree, Ogirisi in Igbo, Adikuru in Hausa and Ewe akoko, Guava (Psidium guajava) is a well known tropical tree which is widely grown for its fruits. 2012;9(1):817 https://doi.org/10.4314/ajtcam.v9i1.12. https://doi.org/10.1016/j.jep.2007.02.011. McCune LM, Johns T. Antioxidant activity in medicinal plants associated with the symptoms of diabetes mellitus used by the indigenous peoples of the north American boreal forest. 2003;84:99104. The effect of the ethanol extract of Justicea. 1978;52:30210. Rats in the 3 different groups received 10, 100 and 1000mg/kg body weight of JCEE orally using oral gavage. Justicia carnea, the Brazilian plume flower, Brazilian-plume, flamingo flower, or jacobinia, is a flowering plant in the family Acanthaceae. 50mg/kg-1200mg/kg treatment relative to control treatment showed varied degree of renal injury that is dose dependent. Materials and Methods Plant material Justicia carnea leaves used in this study were collected from Ozalla Isuofia in Anambra State and identified by Mr. Ozioko One of the side-effects of some orthodox drugs used in the past had been excessive inhibition of the carbohydrate-hydrolyzing enzymes, which in turn leads to abdominal discomfort and. Safety assessment of oral administration of ethanol extract of Justicia Colorimetric assay of catalase. The species Justicia secunda Vahl belongs to the family - Acanthaceae - together with up to 600 other shrubs and herbs species. Safety assessment of Uvaria chamae root extract: acute and subchronic toxicity studies. Justicia carnea (ewe eje) is used by pregnant women to boost the production of red blood cells and cure anemia in pregnancy. 10.9734/ijbcrr/2020/v29i630194. Cut from the stem, some fresh or dried Justicia carnea leaves. The plant is transplanted in the spring. Pharm. I also conduct research on molecular basis of human diseases, linking the pharmacological properties of certain natural products and their mechanisms of actions to the treatment of such diseases. Several medicinal plants such as Xylopia aethiopica [25], Tectona grandis [26] and extracts of M. indica, A. hybridus and T. occidentalis [27] have also been reported to elevate RBC, hemoglobin and packed cell volume. . In a study conducted by Onyeabor and colleagues, the leaf extract of jusiticia carnea reverses the anemic effect of phenylhydrazine on the pack cell volume, red blood cell, and hemoglobin concentrations. Daily intake of the Ewe eje or ajeri can increase the absorption of iron and vitamins, Uses and health benefits of Ewe eje (Justicia carnea leaf). The absorbance was taken at interval of 1min for 3min at 480nm. 2008;108(9):14807. Why urban citizens in developing countries use traditional medicines: the case of suriname. Terms and Conditions, In traditional medicine, justicia carnea is used in treating hepatitis. SOD activity was determined by its ability to inhibit the auto-oxidation of epinephrine determined by the increase in absorbance at 480nm. The effect of the ethanol extract of Justicea carnea (JC) leaves in phenylhydrazine induced-anemia albino rats on haematological and lipid profile parameters was investigated. The findings show that ethanol extracts of Costus afer and Justicia carnea could operate as main antioxidants and free radical scavengers. PDF Biomedical Research 2019; 30 (4): 645-654 ISSN 0970-938X - Allied Academies As for light exposure, keep the plant away from the full sun. It is believed by local consumers in Ghana to possess anti-anaemic effects that boost blood levels in pregnant women, anaemic patients and also . However, watch out for nematodes and spider mites. what are the pros and cons of testosterone replacement therapy? Packed cell volume (PCV) and mean corpuscular volume (MCV) in treated rats with JCEE were statistically unperturbed compared to the control. Effect of Tectona grandis on phenylhydrazine induced anemia in rats. However, caution should be taken as higher dose at 1200mg/kg could cause noticeable tissue injury. Exactly 1.0ml of tissues (liver and kidney) was deproteinised using 0.1ml of 10% TCA and centrifuged at 650g for 5min to obtain supernatant. What this means is that aside fighting anemia, justicia carnea leaves also improves your cardiovascular health by suppressing the tendency for dyslipidemia. Anyone you share the following link with will be able to read this content: Sorry, a shareable link is not currently available for this article. The flowering Justicia plant is a perennial native to the Atlantic Forest eco-regions in eastern Brazil. Research reports it isnt capable of causing kidney and liver damage either but dont eat it raw. The weight of liver and kidney of rats were measured immediately after excising the organs and is presented in Table2. The significant increase in MDA level at 1200mg/kg might be due to the presence of active secondary metabolites in the extracts that could have acted as prooxidant. READ ALSO: How long does it take for Aju mbaise to work. (2017). Evid Based Complement Alternat Med. Olumese FE, Onoagbe IO, Eze GI, Omoruyi FO. In-vivo studies have revealed that radicals produced from these dietary antioxidants are constantly regenerated back to their active form by GSH in the ascorbate glutathione cycle. He earned B.Sc. At the end of 14th day of administration, rats were allowed to fast overnight, sacrificed to collect samples for biochemical analysis and histopathological examination. Hepatoprotective Effect of Methanol Extract of Justicia carnea Leaves

Bright Vachirawit Military Service, Chillicothe Gazette Obituaries Last 3 Days, Head Of Operations Deliveroo, Shaye Saint John Death, How To Clean Breg T Scope Knee Brace, Articles S